Homozygous HLA-C1 is Associated with Reduced Risk of Relapse after HLA-Matched Transplantation in Patients with Myeloid Leukemia.

doi:10.1016/j.bbmt.2017.11.029

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Article

Homozygous HLA-C1 is Associated with Reduced Risk of Relapse after HLA-Matched Transplantation in Patients with Myeloid Leukemia.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Apr 2018

Arima Nobuyoshi, Kanda Junya, Tanaka Junji, Yabe Toshio, Morishima Yasuo, Kim Sung-Won, Najima Yuho, Ozawa Yukiyasu, Eto Tetsuya, Kanamori Heiwa, Mori Takehiko, Kobayashi Naoki, Kondo Tadakazu, Nakamae Hirohisa, Uchida Naoyuki, Inoue Masami, Fukuda Takahiro, Ichinohe Tatsuo, Atsuta Yoshiko, Kanda Yoshinobu

Abstract excerpt

Natural killer (NK) cells assume graft-versus-leukemia alloreactivity after hematopoietic stem cell transplantation (HSCT) through their inhibitory killer cell immunoglobulin-like receptors (KIRs). KIR2D family members recognize HLA-C alleles with Asn80 (HLA-C1) or Lys80 (HLA-C2). The predominance of HLA-C1 over HLA-C2 and the frequent presence of KIR2DL1 are characteristic of Japanese people. We compared...

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PMID: 29197675
DOI: 10.1016/j.bbmt.2017.11.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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