Article
Association between the polymorphism of IL-17A and IL-17F gene with knee osteoarthritis risk: a meta-analysis based on case-control studies.
Journal of orthopaedic surgery and research - 16 Dec 2019
Lu Feifan, Liu Pei, Zhang Qidong, Wang Weiguo, Guo Wanshou
Abstract excerpt
BACKGROUND: Knee osteoarthritis is a joint disease which is characterized by degeneration of articular cartilage and subsequent subchondral bone changes. Polymorphisms of IL-17A/F gene were the recognized candidate genes associated with knee osteoarthritis risk although the results were conflicting. The aim of this study was to determine whether IL-17A(rs2275913) and IL-17F(rs763780) polymorphisms confer...
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