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Article

The genetically determined production of the alarmin eosinophil-derived neurotoxin is reduced in visceral leishmaniasis.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Jan 2018

Blom Kristin, Elshafie Amir I, Jönsson Ulla-Britt, Rönnelid Johan, Håkansson Lena Douhan, Venge Per

Abstract excerpt

Visceral leishmaniasis (VL) is the most severe form of leishmaniasis. Recent findings indicate that dendritic cells have a key role in the defense against the Leishmania parasite and that the activity of this cell may be modified by the eosinophil secretory protein eosinophil-derived neurotoxin (EDN). We hypothesized that the interactions between dendritic cells and EDN might be of importance in the disease...

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Share to Dendritic Cells
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leishmaniasis, Visceral

Share to Polymorphism, Single Nucleotide

Share to Toll-Like Receptor 2

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Identifiers

PMID: 29193305
DOI: 10.1111/apm.12780

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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