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Article

The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Apr 2014

Jönsson Ulla-Britt, Blom Kristin, Stålenheim Gunnemar, Håkansson Lena Douhan, Venge Per

Abstract excerpt

Previous studies showed that the biological activity and the eosinophil content of eosinophil cationic protein (ECP, RNase 3) are determined by single-nucleotide polymorphisms (SNPs) in the ECP (RNase3) gene. In this study, we report the prevalence of a common SNP in the eosinophil protein x/eosinophil-derived neurotoxin (EPX/EDN, RNase2) and the association with the cellular contents of EPX/EDN and ECP. The...

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Source

Identifiers

PMID: 24738159
DOI: 10.1111/apm.12142

Genes

EPX
EPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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