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BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression

26 Nov 2017

Abstract excerpt

The involvement of microRNAs in the control of repressors of human γ-globin gene transcription has been firmly demonstrated, as described for the miR-486-3p mediated down-regulation of BCL11A. On the other hand, we have reported that miR-210 is involved in erythroid differentiation and, possibly, in γ-globin gene up-regulation. In the present study, we have identified the coding sequence of BCL11A as a possible...

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PMID: 29186860
DOI: 10.3390/ijms18122530

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