Article

Assessment of the TGF-β gene and its target miR-1908-5p gene expression and its role in the treatment of beta-thalassemia in Iraqi patients

2024-12-24

Abstract excerpt

Abstract: BACKGROUND: Thalassemia is potentially inherited fatal anemia and can cause health problems when left untreated. Beta-thalassemia is the most severe formula of the illness. Transforming growth factor-beta ( TGF-β ) is a cytokine that has multicellular functions. The miRNAs have been confirmed to play important roles in gene expression regulation during the development of a variety of human diseases. In a...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8e018d1c-0365-51ad-967c-9511a0fac88a
DOI: 10.4103/ijh.ijh_82_24

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Assessment of the TGF-β gene and its target miR-1908-5p gene expression and its role in the treatment of beta-thalassemia in Iraqi patientsDOI 10.4103/ijh.ijh_82_24Read

Investigation of MicroRNA 196a2 polymorphism with Thalassemia Disease among Middle and South Iraqi PopulationSemantic proximity Read

Genotype-Phenotype Correlation of Β-Globin Mutations and Hematological Parameters in Iraqi Β-Thalassemia Patients.Semantic proximity Read

Exploring the crosstalk between long non-coding RNAs and microRNAs to unravel potential prognostic and therapeutic biomarkers in β-thalassemiaSemantic proximity Read

Interleukin gene polymorphisms (IL-6, IL-10, IL-17 a, IL-18) predict beta-thalassemia major susceptibility and inflammatory profiles in Iraqi children: A genetic risk score analysis.Semantic proximity Read

Upregulation of miR-17-3p is associated with HbF in patients with β-thalassemia and induces γ-globin expression by targeting BCL11ASemantic proximity Read

MicroRNAs in β-thalassemia.Semantic proximity Read

Regulation of miR-17-3p on K562 cell proliferation and erythroid differentiation as well as γ-globin expression in patients with β-thalassemiarSemantic proximity Read

Beta-Thalassemia Intermedia: A Single Thalassemia Center Experience from Northeastern Iraq.Semantic proximity Read

Upregulation of miR‑6747‑3p affects red blood cell lineage development and induces fetal hemoglobin expression by targeting BCL11A in β‑thalassemiaSemantic proximity Read

Gene Therapy: A Revolutionary Step in Treating ThalassemiaSemantic proximity Read

Peripheral blood circular RNA circ-0008102 may serve as a novel clinical biomarker in beta-thalassemia patientsSemantic proximity Read