Article
Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD).
International journal of molecular sciences - 25 Nov 2017
Karabegović Irma, Maas Silvana, Medina-Gomez Carolina, Zrimšek Maša, Reppe Sjur, Gautvik Kaare M, Uitterlinden André G, Rivadeneira Fernando, Ghanbari Mohsen
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNA molecules that post-transcriptionally regulate the translation of messenger RNAs. Given the crucial role of miRNAs in gene expression, genetic variants within miRNA-related sequences may affect miRNA function and contribute to disease risk. Osteoporosis is characterized by reduced bone mass, and bone mineral density (BMD) is a major diagnostic proxy to assess...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
