Article
A functional SNP regulated by miR-196a-3p in the 3'UTR of FGF2 is associated with bone mineral density in the Chinese population.
Human mutation - 1 Jun 2017
Zhu Dong-Li, Guo Yan, Zhang Yan, Dong Shan-Shan, Xu Wen, Hao Ruo-Han, Chen Xiao-Feng, Yan Han, Yang Shui-Yun, Yang Tie-Lin
Abstract excerpt
Previous studies have identified FGF2 as a susceptibility gene for osteoporosis in Caucasians. Evaluating the genetic associations in different ethnicities is necessary. Moreover, elucidating the functional mechanism for the susceptibility loci is important to offer new targets for therapeutic studies. Here, we genotyped 10 SNPs in FGF2 and tested for associations with bone mineral density (BMD) in a discovery...
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