Article
The association of common polymorphisms in miR-196a2 with waist to hip ratio and miR-1908 with serum lipid and glucose.
Obesity (Silver Spring, Md.) - 1 Feb 2015
Ghanbari Mohsen, Sedaghat Sanaz, de Looper Hans W J, Hofman Albert, Erkeland Stefan J, Franco Oscar H, Dehghan Abbas
Abstract excerpt
OBJECTIVE: MicroRNAs (miRNAs) have been implicated in the regulation of cardiometabolic disorders. Given the crucial role of miRNAs in gene expression, genetic variation within miRNA genes is expected to affect miRNA function and substantially contribute to disease risk. METHODS: 2,320 variants in miRNA-encoding sequences were systematically retrieved, and their associations with 17 cardiometabolic...
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