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Article

Polymorphisms in predicted miRNA binding sites and osteoporosis.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Jan 2011

Lei Shu-Feng, Papasian Christopher J, Deng Hong-Wen

Abstract excerpt

MicroRNAs (miRNAs) regulate posttranscriptional gene expression usually by binding to 3'-untranslated regions (3'-UTRs) of target message RNAs (mRNAs). Hence genetic polymorphisms on 3'-UTRs of mRNAs may alter binding affinity between miRNAs target 3'-UTRs, thereby altering translational regulation of target mRNAs and/or degradation of mRNAs, leading to differential protein expression of target genes. Based on a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20641033
DOI: 10.1002/jbmr.186
PMCID: PMC3179316

Genes

FGF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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