Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mode of Action and Heterologous Expression of the Natural Product Antibiotic Vancoresmycin

29 Nov 2017

Abstract excerpt

Antibiotics that interfere with the bacterial cytoplasmic membrane have long-term potential for the treatment of infectious diseases as this mode of action is anticipated to result in low resistance frequency. Vancoresmycin is an understudied natural product antibiotic consisting of a terminal tetramic acid moiety fused to a linear, highly oxygenated, stereochemically complex polyketide chain. Vancoresmycin shows...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genomics and Phylogenetic Studies
Share to Microbial Natural Products and Biosynthesis
Share to Plant-Microbe Interactions and Immunity

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29185696
DOI: 10.1021/acschembio.7b00733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mode of Action and Heterologous Expression of the Natural Product Antibiotic VancoresmycinPMID 29185696Read ↗

Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species.Semantic proximity Read ↗

Olikomycin A–A Novel Calcium‐Dependent Lipopeptide with Antibiotic Activity Against Multidrug‐Resistant BacteriaSemantic proximity Read ↗

Profiling the <i>in vitro</i> and <i>in vivo</i> activity of streptothricin-F against carbapenem-resistant Enterobacterales: a historic scaffold with a novel mechanism of actionSemantic proximity Read ↗

Biosynthesis and Engineered Overproduction of Everninomicins with Promising Activity against Multidrug-Resistant BacteriaSemantic proximity Read ↗

A High-Throughput Approach To Identify Compounds That Impair Envelope Integrity in Escherichia coli.Semantic proximity Read ↗

A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug TransporterSemantic proximity Read ↗

Sattahipmycin, a Hexacyclic Xanthone Produced by a Marine-Derived StreptomycesSemantic proximity Read ↗

Recent Trends in Synthesis of Chloramphenicol New DerivativesSemantic proximity Read ↗

Antibiotic export: transporters involved in the final step of natural product productionSemantic proximity Read ↗

How to Enter a Bacterium: Bacterial Porins and the Permeation of AntibioticsSemantic proximity Read ↗

Inhibition of Multiple Staphylococcal Growth States by a Small Molecule that Disrupts Membrane Fluidity and VoltageSemantic proximity Read ↗

Two of a Kind--The Biosynthetic Pathways of Chlorotonil and Anthracimycin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.