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Antibiotic export: transporters involved in the final step of natural product production

9 Apr 2019

Abstract excerpt

In the fight against antimicrobial resistance (AMR), antibiotic biosynthetic gene clusters are constantly being discovered. These clusters often include genes for membrane transporters that are involved in the export of the produced natural product during biosynthesis and/or subsequent resistance through active efflux. Despite transporter genes being integral parts of these clusters, study of the function of...

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PMID: 30964430
DOI: 10.1099/mic.0.000794

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