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Recent Trends in Synthesis of Chloramphenicol New Derivatives

31 Mar 2021

Abstract excerpt

during the "golden era" of antibiotic discovery, nowadays has limited clinical potential due to adverse side effects and frequent antimicrobial resistance. Numerous CAM analogs were synthesized in order to find the derivatives with improved pharmacological properties and activity on resistant bacterial strains. This work aims to summarize the most recent achievements in obtaining new CAM analogs reported during...

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PMID: 33807439
DOI: 10.3390/antibiotics10040370

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