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Article

USP44+ Cancer Stem Cell Subclones Contribute to Breast Cancer Aggressiveness by Promoting Vasculogenic Mimicry.

Molecular cancer therapeutics - 1 Sept 2015

Liu Tieju, Sun Baocun, Zhao Xiulan, Li Yanlei, Zhao Xueming, Liu Ying, Yao Zhi, Gu Qiang, Dong Xueyi, Shao Bing, Lin Xian, Liu Fang, An Jindan

Abstract excerpt

Vasculogenic mimicry (VM), a newly defined pattern of tumor blood supply, describes the functional plasticity of aggressive cancer cells that form vascular networks. In our previous study, breast cancer stem cells (CSC) were shown to potentially participate in VM formation. In this study, breast CSCs presented centrosome amplification (CA) phenotype and ubiquitin-specific protease 44 (USP44) upregulation. USP44...

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PMID: 26232424
DOI: 10.1158/1535-7163.MCT-15-0114-T

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USP44

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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