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NEDD4 Plays Roles in the Maintenance of Breast Cancer Stem Cell Characteristics

2 Sept 2020

Abstract excerpt

Triple-negative breast cancer (TNBC) is the most aggressive type with poor prognosis among the breast cancers and has a high population of cancer stem cells (CSCs), which are the main target to cure and inhibit TNBC. In this study, we examined the role of neural precursor cell expressed developmentally downregulated protein 4 (NEDD4) in the proliferation, migration, and CSC characteristics of MDA-MB-231, a TNBC...

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PMID: 33014839
DOI: 10.3389/fonc.2020.01680

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