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Article

Live imaging analysis of human gastric epithelial spheroids reveals spontaneous rupture, rotation and fusion events.

Cell and tissue research - 1 Feb 2018

Sebrell T Andrew, Sidar Barkan, Bruns Rachel, Wilkinson Royce A, Wiedenheft Blake, Taylor Paul J, Perrino Brian A, Samuelson Linda C, Wilking James N, Bimczok Diane

Abstract excerpt

Three-dimensional cultures of primary epithelial cells including organoids, enteroids and epithelial spheroids have become increasingly popular for studies of gastrointestinal development, mucosal immunology and epithelial infection. However, little is known about the behavior of these complex cultures in their three-dimensional culture matrix. Therefore, we performed extended time-lapse imaging analysis (up to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 29178040
DOI: 10.1007/s00441-017-2726-5
PMCID: PMC5785432

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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