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Article

Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche.

PLoS pathogens - 1 May 2009

Tan Shumin, Tompkins Lucy S, Amieva Manuel R

Abstract excerpt

Helicobacter pylori (Hp) intimately interacts with the gastric epithelial surface and translocates the virulence factor CagA into host cells in a contact-dependent manner. To study how Hp benefits from interacting with the cell surface, we developed live-cell microscopy methods to follow the fate of individual bacteria on the cell surface and find that Hp is able to replicate and form microcolonies directly over...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19412339
DOI: 10.1371/journal.ppat.1000407
PMCID: PMC2669173

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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