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Recapitulating the Drifting and Fusion of Two-Generation Spheroids on Concave Agarose Microwells

26 Jul 2023

Abstract excerpt

Cells with various structures and proteins naturally come together to cooperate in vivo. This study used cell spheroids cultured in agarose micro-wells as a 3D model to study the movement of cells or spheroids toward other spheroids. The formation dynamics of tumor spheroids and the interactions of two batches of cells in the agarose micro-wells were studied. The results showed that a concave bottom micro-well...

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PMID: 37569343
DOI: 10.3390/ijms241511967

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