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Gastric cancer multicellular spheroid analysis by two-photon microscopy

9 Feb 2022

Abstract excerpt

Gastric cancer (GC) is highly deadly. Three-dimensional (3D) cancer cell cultures, known as spheroids, better mimic tumor microenvironment (TME) than standard 2D cultures. Cancer-associated fibroblasts (CAF), a major cellular component of TME, promote or restrain cancer cell proliferation, invasion and resistance to drugs. We established spheroids from two human GC cell lines mixed with human primary CAF....

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PMID: 35774334
DOI: 10.1364/boe.450518

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