Article
Identification of a basidiomycete-specific Vilse-like GTPase activating proteins (GAPs) and its roles in the production of virulence factors in Cryptococcus neoformans.
FEMS yeast research - 1 Dec 2017
Rahim Kashif, Huo Liang, Li Chenxi, Zhang Ping, Basit Abdul, Xiang Biyun, Ting Bie, Hao Xiaoran, Zhu Xudong
Abstract excerpt
Cryptococcus neoformans is a basidiomycetous pathogenic yeast that causes fatal infections in both immunocompetent and immunocompromised patients. Regulation on the production of its virulence factors is not fully understood. Here we reported the characterization of a gene, named CVH1(CNA06260), encoding a Drosophila Vilse-like RhoGAP homolog, which is hallmarked by three conserved functional domains: WW, MyTH4...
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