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Gene, virulence and related regulatory mechanisms in Cryptococcus gattii.

Acta biochimica et biophysica Sinica - 25 May 2022

Huang Yemei, Zang Xuelei, Yang Chen, Deng Hengyu, Ma Xidong, Xie Mei, Zhou Meng, Song Jialin, Xue Xinying

Abstract excerpt

Cryptococcus gattii is a kind of basidiomycetous yeast, which grows in human and animal hosts. C. gattii has four distinct genomes, VGI/AFLP4, VGII/AFLP6, VGIII/AFLP5, and VGIV/AFLP7. The virulence of C. gattii is closely associated with genotype and related stress-signaling pathways, but the pathogenic mechanism of C. gattii has not been fully identified. With the development of genomics and transcriptomics, the...

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PMID: 35593469
DOI: 10.3724/abbs.2022029
PMCID: PMC9828318

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