Article
Gene expression data reveal common pathways that characterize the unifocal nature of ovarian cancer.
American journal of obstetrics and gynecology - 1 Dec 2013
Marchion Douglas C, Xiong Yin, Chon Hye Sook, Al Sawah Entidhar, Bou Zgheib Nadim, Ramirez Ingrid J, Abbasi Forough, Stickles Xiaomang B, Judson Patricia L, Hakam Ardeshir, Gonzalez-Bosquet Jesus, Wenham Robert M, Apte Sachin M, Berglund Anders E, Lancaster Johnathan M
Abstract excerpt
OBJECTIVE: The objective of the study was to evaluate the biological validity of ovarian cancer (OVCA) screening and early detection efforts and to characterize signaling pathways associated with human cancer metastasis and patient survival. STUDY DESIGN: Using genome-wide expression profiling and deoxyribonucleic acid sequencing, we compared pelvic and matched extrapelvic implants from 30 patients with...
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