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Article

The role of the ATP-Binding Cassette A1 (ABCA1) in neurological disorders: a mechanistic review

3 Jul 2023

Abstract excerpt

INTRODUCTION: Cholesterol homeostasis is critical for normal brain function. It is tightly controlled by various biological elements. ATP-binding cassette transporter A1 (ABCA1) is a membrane transporter that effluxes cholesterol from cells, particularly astrocytes, into the extracellular space. The recent studies pertaining to ABCA1's role in CNS disorders were included in this study. AREAS COVERED: In this...

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PMID: 37428709
DOI: 10.1080/14728222.2023.2235718

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