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Role of ABC Transporters in the Pathogenesis of Alzheimer’s Disease

11 Oct 2012

Abstract excerpt

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common form of age-related dementia that begins with memory loss and progresses to include severe cognitive impairment. A major pathological hallmark of AD is the accumulation of beta amyloid peptide (Aβ) in senile plaques in the brain of AD patients. The exact mechanism by which AD takes place remains unknown. However, an...

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PMID: 23181169
DOI: 10.1021/cn300077c

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