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Article

Family-based analysis of -675 4G/5G polymorphism in the PAI-1 gene of polycystic ovary syndrome in Chinese population.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Oct 2022

Song Xiaocui, Ge Li, Wang Dongsha, Li Li, Ma Dongmei, Li Xiu, Song Xiaocui

Abstract excerpt

Previous studies have shown that 4G/5G polymorphism in promoter region of plasminogen activator inhibitor-1 (PAI-1) gene can affect insulin sensitivity by elevating the level and activity of plasma PAI-1. In order to elucidate the relationship between the polymorphism of PAI-1 gene and polycystic ovary syndrome (PCOS), we used transmission disequilibrium test (TDT) to study the family of PCOS. Eight hundred and...

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PMID: 36065507
DOI: 10.1080/01443615.2022.2114326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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