Article
GSTA1 Expression Is Correlated With Aldosterone Level in KCNJ5-Mutated Adrenal Aldosterone-Producing Adenoma.
The Journal of clinical endocrinology and metabolism - 1 Mar 2018
Li Xintao, Wang Baojun, Tang Lu, Zhang Yu, Chen Luyao, Gu Liangyou, Zhang Fan, Ouyang Jinzhi, Zhang Xu
Abstract excerpt
Context: KCNJ5 mutation is a major cause of aldosterone-producing adenomas (APAs). The development of APA apart from KCNJ5 mutation is less investigated. Objective: To investigate other mechanisms affecting aldosterone secretion apart from KCNJ5. Patients and Methods: Six pairs of KCNJ5-mutated, high and low aldosterone-secreting APAs, five non-KCNJ5-mutated APAs, and four normal adrenal glands were assayed by...
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