Article
RNA metabolism is the primary target of formamide in vivo.
Scientific reports - 21 Nov 2017
Hoyos-Manchado Rafael, Reyes-Martín Félix, Rallis Charalampos, Gamero-Estévez Enrique, Rodríguez-Gómez Pablo, Quintero-Blanco Juan, Bähler Jürg, Jiménez Juan, Tallada Víctor A
Abstract excerpt
The synthesis, processing and function of coding and non-coding RNA molecules and their interacting proteins has been the focus of a great deal of research that has boosted our understanding of key molecular pathways that underlie higher order events such as cell cycle control, development, innate immune response and the occurrence of genetic diseases. In this study, we have found that formamide preferentially...
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