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Article

Tonicity-Responsive Enhancer-Binding Protein Mediates Hyperglycemia-Induced Inflammation and Vascular and Renal Injury.

Journal of the American Society of Nephrology : JASN - 1 Feb 2018

Choi Soo Youn, Lim Sun Woo, Salimi Shabnam, Yoo Eun Jin, Lee-Kwon Whaseon, Lee Hwan Hee, Lee Jun Ho, Mitchell Braxton D, Sanada Satoru, Parsa Afshin, Kwon Hyug Moo

Abstract excerpt

Diabetic nephropathy (DN) has become the single leading cause of ESRD in developed nations. Bearing in mind the paucity of effective treatment for DN and progressive CKD, novel targets for treatment are sorely needed. We previously reported that increased activity of tonicity-responsive enhancer-binding protein (TonEBP) in monocytes was associated with early DN in humans. We now extend these findings by testing...

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Source

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Identifiers

PMID: 29158465
DOI: 10.1681/ASN.2017070718
PMCID: PMC5791077

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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