Article

Diabetes-Induced Vascular Dysfunction and Stemness Decline Investigated via Transcription Factor-Driven Genetic Switches

2024-05-30

Abstract excerpt

<title>Abstract</title><p><bold>Background:</bold>Diabetes mellitus precipitates cardiovascular complications through hyperglycemia, oxidative stress, and inflammation, disrupting vascular cell function. This dysfunction involves altered regulation of transcription factors like Nrf2 and FOXP1, leading to endothelial dysfunction, impaired angiogenesis, and faulty vascular remodeling. Additionally, diabetes reduces...

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Literature Corpus work: 32b5e59d-af32-515d-8a7e-62f918cde290
DOI: 10.21203/rs.3.rs-4498525/v1

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