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Genetic polymorphisms of the P2X7 gene associated with susceptibility to and prognosis of pulmonary tuberculosis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Sept 2017

Zheng Xianzhi, Li Tiecheng, Chen Yongzhong, Pan Hongqiu, Zhang Zhihai, Dai Yaoyao, Wang Jianming

Abstract excerpt

In this population-based case control study, we recruited 1601 pulmonary tuberculosis cases and 1526 healthy controls, aiming to investigate the association of genetic polymorphisms of the P2X7 gene with the susceptibility to and prognosis of pulmonary tuberculosis in a Chinese Han population. Five single-nucleotide polymorphisms (SNPs) in the P2X7 gene were genotyped. The odds ratio (OR) or relative risk (RR)...

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PMID: 28495473
DOI: 10.1016/j.meegid.2017.05.003

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