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Article

PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress.

Scientific reports - 17 Nov 2017

Carpino Guido, Pastori Daniele, Baratta Francesco, Overi Diletta, Labbadia Giancarlo, Polimeni Licia, Di Costanzo Alessia, Pannitteri Gaetano, Carnevale Roberto, Del Ben Maria, Arca Marcello, Violi Francesco, Angelico Francesco, Gaudio Eugenio

Abstract excerpt

Pathogenesis of non-alcoholic fatty liver disease (NAFLD) is influenced by predisposing genetic variations, dysmetabolism, systemic oxidative stress, and local cellular and molecular cross-talks. Patatin-like phospholipase domain containing 3 (PNPLA3) gene I148M variant is a known determinant of NAFLD. Aims were to evaluate whether PNPLA3 I148M variant was associated with a specific histological pattern, hepatic...

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Identifiers

PMID: 29150621
DOI: 10.1038/s41598-017-15943-z
PMCID: PMC5693899

Genes

PNPLA3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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PNPLA3 variant and portal/periportal histological pattern in patients with biopsy-proven non-alcoholic fatty liver disease: a possible role for oxidative stress.PMID 29150621Read ↗

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