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Article

Effects of regulatory BC1 RNA deletion on synaptic plasticity, learning, and memory.

Learning & memory (Cold Spring Harbor, N.Y.) - 1 Dec 2017

Chung Ain, Dahan Nessy, Alarcon Juan Marcos, Fenton André A

Abstract excerpt

Nonprotein coding dendritic BC1 RNA regulates translation of mRNAs in neurons. We examined two lines of BC1 knockout mice and report that loss of BC1 RNA exaggerates group I mGluR-stimulated LTD of the Schaffer collateral synapse, with one of the lines showing a much more enhanced DHPG-induced LTD than the other. When the animals were given the hippocampus-synaptic plasticity-dependent active place avoidance...

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Identifiers

PMID: 29142061
DOI: 10.1101/lm.045617.117
PMCID: PMC5688958

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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