Article
Calmodulin regulates synaptic plasticity in the anterior cingulate cortex and behavioral responses: a microelectroporation study in adult rodents.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 10 Sept 2003
Wei Feng, Xia Xia-Ming, Tang Jianrong, Ao Hushan, Ko Shanelle, Liauw Jason, Qiu Chang-Shen, Zhuo Min
Abstract excerpt
We developed a microelectroporation method for the transfer of genes into neurons in the cerebral cortex of adult rodents, both rats and mice. We selectively expressed either green-fluorescent protein (GFP) or a Ca2+-binding deficient calmodulin (CaM) mutant in the anterior cingulate cortex (ACC). In mice that expressed GFP, positive neuronal cell bodies were found specifically at the injection site in the ACC....
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