Article
DC-SIGN Polymorphisms Associate with Risk of Hepatitis C Virus Infection Among Men who Have Sex with Men but not Among Injecting Drug Users.
The Journal of infectious diseases - 17 Jan 2018
Steba Gaby S, Koekkoek Sylvie M, Vanhommerig Joost W, Brinkman Kees, Kwa David, Van Der Meer Jan T M, Prins Maria, Berkhout Ben, Tanck Michael, Paxton William A, Molenkamp Richard, Schinkel Janke
Abstract excerpt
We aimed to identify whether genetic polymorphisms within L-SIGN or DC-SIGN correlate with hepatitis C virus (HCV) susceptibility. A men who have sex with men (MSM) and an injecting drug users (IDU) cohort of HCV cases and multiple-exposed uninfected controls were genotyped for numerous L-SIGN and DC-SIGN polymorphisms. DC-SIGN single nucleotide polymorphisms (SNPs) -139, -871, and -939 correlated with HCV...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
