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Article

Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients.

International journal of cancer - 1 Apr 2018

Yamauchi Masami, Urabe Yuji, Ono Atsushi, Miki Daiki, Ochi Hidenori, Chayama Kazuaki

Abstract excerpt

Understanding the molecular changes in tumors in response to anti-VEGF chemotherapy is crucial for optimization of the treatment strategy for metastatic colorectal cancer. We prospectively investigated changes in the amount and constitution of circulating tumor DNA (ctDNA) in serial peripheral blood samples during chemotherapy. Sixty-one plasma samples taken at different time points (baseline, remission, and...

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Identifiers

PMID: 29134647
DOI: 10.1002/ijc.31154

Genes

MAF
CREBBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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