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Article

Circulating Tumor DNA in Precision Oncology and Its Applications in Colorectal Cancer.

International journal of molecular sciences - 18 Apr 2022

Arisi Maria F, Dotan Efrat, Fernandez Sandra V

Abstract excerpt

Circulating tumor DNA (ctDNA) is a component of cell-free DNA (cfDNA) that is shed by malignant tumors into the bloodstream and other bodily fluids. ctDNA can comprise up to 10% of a patient's cfDNA depending on their tumor type and burden. The short half-life of ctDNA ensures that its detection captures tumor burden in real-time and offers a non-invasive method of repeatedly evaluating the genomic profile of a...

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Identifiers

PMID: 35457259
DOI: 10.3390/ijms23084441
PMCID: PMC9024503

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