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Article

Mutational evolution after chemotherapy-progression in metastatic colorectal cancer revealed by circulating tumor DNA analysis.

International journal of cancer - 1 Aug 2023

Kim Sheehyun, Cha Yongjun, Lim Yoojoo, Roh Hanseong, Kang Jun-Kyu, Lee Kyung-Hun, Kim Min Jung, Park Ji Won, Ryoo Seung-Bum, Kim Hwang-Phill, Jeong Seung-Yong, Park Kyu Joo, Han Sae-Won, Kim Tae-You

Abstract excerpt

Emerging new mutations after treatment can provide clues to acquired resistant mechanisms. Circulating tumor DNA (ctDNA) sequencing has enabled noninvasive repeated tumor mutational profiling. We aimed to investigate newly emerging mutations in ctDNA after disease progression in metastatic colorectal cancer (mCRC). Blood samples were prospectively collected from mCRC patients receiving palliative chemotherapy...

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PMID: 37194418
DOI: 10.1002/ijc.34558

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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