Article

Identification of an immune gene expression signature associated with favorable clinical features in Treg-enriched patient tumor samples

2018-01-11

Abstract excerpt

Immune heterogeneity within the tumor microenvironment undoubtedly adds several layers of complexity to our understanding of drug sensitivity and patient prognosis across various cancer types. Within the tumor microenvironment, immunogenicity is a favorable clinical feature in part driven by the antitumor activity of CD8+ T cells. However, tumors often inhibit this antitumor activity by exploiting the suppressive...

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Literature Corpus work: 7e293d63-78d7-5165-a739-b1a9b57908d1
DOI: 10.1101/246603

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