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Article

Gene expression signatures of neuroendocrine prostate cancer and primary small cell prostatic carcinoma

13 Nov 2017

Abstract excerpt

BACKGROUND: Neuroendocrine prostate cancer (NEPC) may be rising in prevalence as patients with advanced prostate cancer potentially develop resistance to contemporary anti-androgen treatment through a neuroendocrine phenotype. While prior studies comparing NEPC and prostatic adenocarcinoma have identified important candidates for targeted therapy, most have relied on few NEPC patients due to disease rarity,...

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PMID: 29132337
DOI: 10.1186/s12885-017-3729-z

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