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Article

The association of polymorphic markers Arg399Gln of XRCC1 gene, Arg72Pro of TP53 gene and T309G of MDM2 gene with breast cancer in Kyrgyz females.

BMC cancer - 13 Nov 2017

Isakova Jainagul, Talaibekova Elnura, Aldasheva Nazira, Vinnikov Denis, Aldashev Almaz

Abstract excerpt

BACKGROUND: The association of genes XRCC1, TP53 and MDM2 with breast cancer (BC) has never been tested in Kyrgyz population. We, therefore, aimed to identify an association of alleles and genotypes of polymorphic markers Arg399Gln of gene XRCC1, Arg72Pro of gene TP53, and T309G of gene MDM2 with the risk of BC in Kyrgyz women. METHODS: This was a case-control study of 219 women of Kyrgyz origin with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-mdm2

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Share to X-ray Repair Cross Complementing Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 29132330
DOI: 10.1186/s12885-017-3762-y
PMCID: PMC5683588

Genes

XRCC1
MDM2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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