Article
[Association of the Arg399Gln polymorphisms of the XRCC1 gene with breast cancer risk in Kyrgiz women].
Voprosy onkologii - 1 Jan 2015
Isakova Zh T, Makieva K B, E T Talaibekova, Asambaeva D A, Sultangazieva B B, Aldashev A A
Abstract excerpt
There were examined 219 women of Kyrgyz nationality (mean age 51 ± 9.7 years). 117 female with breast cancer (BC) and 102 apparently health controls. The diagnosis of breast cancer was confirmed histologically. DNA was prepared from whole blood samples. XRCC1 genotypes Arg399Gln were examined using polymerase chain reaction-restriction enzyme polymorphism (PCR-RFLP). The frequency of the variant 399Gln allele and...
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