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Article

Development of amplicon deep sequencing markers and data analysis pipeline for genotyping multi-clonal malaria infections.

BMC genomics - 13 Nov 2017

Lerch Anita, Koepfli Cristian, Hofmann Natalie E, Messerli Camilla, Wilcox Stephen, Kattenberg Johanna H, Betuela Inoni, O'Connor Liam, Mueller Ivo, Felger Ingrid

Abstract excerpt

BACKGROUND: Amplicon deep sequencing permits sensitive detection of minority clones and improves discriminatory power for genotyping multi-clone Plasmodium falciparum infections. New amplicon sequencing and data analysis protocols are needed for genotyping in epidemiological studies and drug efficacy trials of P. falciparum. METHODS: Targeted sequencing of molecular marker csp and novel marker cpmp was conducted...

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Identifiers

PMID: 29132317
DOI: 10.1186/s12864-017-4260-y
PMCID: PMC5682641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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