Article
Genotyping Plasmodium falciparum gametocytes using amplicon deep sequencing.
Malaria journal - 6 Apr 2024
Vareta Jimmy, Horstman Natalie A, Adams Matthew, Seydel Karl B, McCann Robert S, Cohee Lauren M, Laufer Miriam K, Takala-Harrison Shannon
Abstract excerpt
BACKGROUND: Understanding the dynamics of gametocyte production in polyclonal Plasmodium falciparum infections requires a genotyping method that detects distinct gametocyte clones and estimates their relative frequencies. Here, a marker was identified and evaluated to genotype P. falciparum mature gametocytes using amplicon deep sequencing. METHODS: A data set of polymorphic regions of the P. falciparum genome...
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