Article
Fish Macrophages Show Distinct Metabolic Signatures Upon Polarization.
Frontiers in immunology - 1 Jan 2020
Wentzel Annelieke S, Janssen Joëlle J E, de Boer Vincent C J, van Veen Wouter G, Forlenza Maria, Wiegertjes Geert F
Abstract excerpt
Macrophages play important roles in conditions ranging from host immune defense to tissue regeneration and polarize their functional phenotype accordingly. Next to differences in the use of L-arginine and the production of different cytokines, inflammatory M1 macrophages and anti-inflammatory M2 macrophages are also metabolically distinct. In mammals, M1 macrophages show metabolic reprogramming toward glycolysis,...
Topics
Join the communities discussing this publication.