Article
Dissonant response of M0/M2 and M1 bone-marrow-derived macrophages to RhoA pathway interference.
Cell and tissue research - 1 Dec 2016
Liu Yianzhu, Chen Wenhao, Minze Laurie J, Kubiak Jacek Z, Li Xian C, Ghobrial Rafik M, Kloc Malgorzata
Abstract excerpt
Macrophages have a multitude of functions in innate and adaptive immune response and organ and tissue homeostasis. Many experimental studies are performed on bone-marrow-derived macrophages differentiated in vitro into M1 (inflammatory) and M2 (anti-inflammatory) subtypes that express different molecular markers pertaining to their prospective functions. Macrophage phenotype, polarity and functions depend on the...
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