Article
An empirical Bayes test for allelic-imbalance detection in ChIP-seq.
Biostatistics (Oxford, England) - 1 Oct 2018
Zhang Qi, Keles Sündüz
Abstract excerpt
Chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) has enabled discovery of genomic regions enriched with biological signals such as transcription factor binding and histone modifications. Allelic-imbalance (ALI) detection is a complementary analysis of ChIP-seq data for associating biological signals with single nucleotide polymorphisms (SNPs). It has been successfully used in...
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