Article
The effects of runs-of-homozygosity on pig domestication and breeding.
BMC genomics - 6 Jan 2025
Tao Lin, Liu Hang, Adeola Adeniyi C, Xie Hai-Bing, Feng Shu-Tang, Zhang Ya-Ping
Abstract excerpt
BACKGROUND: Since their domestication, recent inbreeding together with intensive artificial selection and population bottlenecks have allowed the prevalence of deleterious mutations and the increase of runs-of-homozygosity (ROH) in domestic pigs. This makes pigs a good model to understand the genetic underpinnings of inbreeding depression. RESULTS: Here we integrated a comprehensive dataset comprising 7239...
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