Article
PFI1785w: A highly conserved protein associated with pregnancy associated malaria.
PloS one - 1 Jan 2017
Kamaliddin Claire, Salnot Virginie, Leduc Marjorie, Ezinmegnon Sem, Broussard Cédric, Fievet Nadine, Deloron Philippe, Guillonneau François, Bertin Gwladys I
Abstract excerpt
Pregnancy-associated malaria (PAM) is one of the severe forms of Plasmodium falciparum infection. The main antigen VAR2CSA is the target of vaccine development. However, the large size of VAR2CSA protein and its high degree of variability limit to the efficiency of the vaccination. Using quantitative mass spectrometry method, we detected and quantified proteotypic peptides from 5 predicted PAM associated...
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