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Article

Isolation of T-cell clones with specificity for arterial antigen from spontaneously hypertensive rats.

Journal of hypertension - 1 Dec 1993

Ofosu-Appiah W, Ruggiero C, Huang L Y

Abstract excerpt

OBJECTIVE: It has been postulated that hypertension in the spontaneously hypertensive rat (SHR) results from autoimmune damage to the SHR vasculature. The objective of this study was to isolate autoreactive T-cells specific for arterial antigens, and to characterize these cells. DESIGN: The presence of autoreactive T-cells in the SHR has not been studied previously. Lymphocytes were isolated from spleens obtained...

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Identifiers

PMID: 7907630
DOI: 10.1097/00004872-199312000-00002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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