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Article

NLRP3 polymorphisms and response to interferon-beta in multiple sclerosis patients.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Oct 2018

Malhotra Sunny, Sorosina Melissa, Río Jordi, Peroni Silvia, Midaglia Luciana, Villar Luisa M, Álvarez-Cermeño José C, Schroeder Ina, Esposito Federica, Clarelli Ferdinando, Zettl Uwe K, Lechner-Scott Jeannette, Spataro Nino, Navarro Arcadi, Comi Giancarlo, Montalban Xavier, Martinelli-Boneschi Filippo, Comabella Manuel

Abstract excerpt

We aimed to investigate whether NLR family, pyrin domain containing 3 (NLRP3) polymorphisms are associated with the response to interferon-beta (IFNβ) in multiple sclerosis (MS) patients. A total of 14 NLRP3 polymorphisms were genotyped in a cohort of 665 relapsing-remitting MS patients recruited across 5 centers and classified into responders and non-responders according to clinical-radiological criteria after 1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29117789
DOI: 10.1177/1352458517739137

Genes

NLRP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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